Found 1352 of ic50 for POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-2
having polymerids = 7858,50006570,204,9866,231 and
complexids = 50000914
having polymerids = 7858,50006570,204,9866,231 and
complexids = 50000914
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.0480nMAssay Description:Inhibition of TNKS1/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by dual-glo lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0882nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0982nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.179nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.191nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 0.193nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 0.196nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.204nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
Affinity DataIC50: 0.206nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Affinity DataIC50: 0.227nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 0.237nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.264nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human GST-tagged tankyrase 2 autophosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.292nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 0.294nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...More data for this Ligand-Target Pair